PICO

PICO Anticipation

A review of EMA approvals, clinical guidelines, HTA decisions, and real-world treatment patterns will identify the evidence needed to inform the PICO requirements for each country.

EMA approvals
Review identified evidence to inform anticipated PICO requirements
Symmetron's living JCA database
Clinical guidelines
Review of key clinical guidelines and treatment pathways across EU MS
HTA landscape
Review previous JCA and HTA submissions across EU MS in target indication
Real-world treatment patterns
Review identified evidence to inform anticipated PICO requirements
Evidence assessment
Review identified evidence to inform anticipated PICO requirements
Targeted use of Al to support
identification, screening and synthesis of evidence