Services

Health Technology Assessment

Strategic and operational support for reimbursement applications, from global evidence planning through to local adaptation.

  • Strategic review of value propositions and supporting evidence to align with local HTA requirements. 
  • End-to-end strategic partnership for HTA submissions, from early planning through to post-submission support and local adaptations.
  • Preparation of supporting materials including global value dossiers, evidence summaries, and objection handling documents, translating complex evidence into clear and credible value communication.
  • Adaptation of global materials to local HTA standards and country-specific requirements while maintaining consistency across markets.
  • Submission support including strategic workshops, mock committee meetings and local technical engagement preparation. 
Other services include:
Rare diseases
Gaining reimbursement for a drug targeting a rare disease
Author
Date
Neurology & mental health
Evaluating the cost-effectiveness of a medical device
Author
Date
Respiratory
Modelling survival after the clinical trials have ended
Author
Date
Policy and methods
Developing a framework for analysing the impact of patient-centred outcomes for achieving reimbursement in the UK
Author
Date
Cardiometabolic health
Evaluating the cost-effectiveness of a diagnostic device
Author
Date
Oncology
Overcoming limited evidence to gain reimbursement for a blockbuster oncology drug
Author
Date
Dermatology
Overcoming the short-term bias in clinical evidence to compare long-term efficacy of psoriasis treatments
Author
Date
Dermatology
Validating comparisons of disease treatments in the absence of head-to-head trials
Author
Date

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“The team went above and beyond our expectations for our project. We were grateful that Symmetron was able to meet our deadlines, and to deliver a very large volume of work”
“One of the most efficient partnerships I’ve had with an external group.”
“Symmetron has expertise in all areas, including project management, SLRs, NMAs, economic modelling and a good relationship with the medical writer.”
“Our expectations were met, and the project was handled at the highest level."
Gaining reimbursement for a drug targeting a rare disease
Gaining reimbursement for a drug targeting a rare disease
Evaluating the cost-effectiveness of a medical device
Evaluating the cost-effectiveness of a medical device
Modelling survival after the clinical trials have ended
Modelling survival after the clinical trials have ended
Developing a framework for analysing the impact of patient-centred outcomes for achieving reimbursement in the UK
Developing a framework for analysing the impact of patient-centred outcomes for achieving reimbursement in the UK
Evaluating the cost-effectiveness of a diagnostic device
Evaluating the cost-effectiveness of a diagnostic device
Overcoming limited evidence to gain reimbursement for a blockbuster oncology drug
Overcoming limited evidence to gain reimbursement for a blockbuster oncology drug
Overcoming the short-term bias in clinical evidence to compare long-term efficacy of psoriasis treatments
Overcoming the short-term bias in clinical evidence to compare long-term efficacy of psoriasis treatments
Validating comparisons of disease treatments in the absence of head-to-head trials
Validating comparisons of disease treatments in the absence of head-to-head trials